SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI
| Main Authors: | Hardi, Jaya, Nurakhirawati, Nurakhirawati, Ridhay, Ahmad, Musdalifah, Musdalifah |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Chemistry Department
, 2017
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| Online Access: |
http://jurnal.untad.ac.id/jurnal/index.php/kovalen/article/view/8231 http://jurnal.untad.ac.id/jurnal/index.php/kovalen/article/view/8231/6525 |
Daftar Isi:
- The research about the influence of NaOH concentrations and reaction temperature to O-Carboxymethyl Chitosan (O-CMC) synthesis and it is antibacterial application was done. This research intent on detect NaOH concentration and reaction temperature that resulting of O-CMC with highest of yield, solubility, and substitution degrees, and also to find out FTIR spectrum and antibacterial activity of O-CMC. The produce of O-CMC was done by using a Completely Randomized Design (CRD) with the variation of NaOH concentration of 20%, 30%, 40%, 50%, and 60%, and also reaction temperature of 20, 30, and 40oC. The result was showed that on the NaOH concentration of 60% (w/v) and temperature of 30oC was resulted highest of yield, solubility, and substitution degrees of 41.5%, 31 g/L, and 0.67, respectively. FTIR spectrum was showed that bending vibration of primary amine (-NH2) give two bands for O-CMC. The broadest inhibition area of O-CMC (1.43 cm) was showed on Salmonella sp.Keywords: chitosan, O-CMC, substitution degree, antibacterial