PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP KUALITAS DAN KUANTITAS SPERMATOZOA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR WISTAR YANG DIBERI PAPARAN ASAP ROKOK
Daftar Isi:
- Background: Infertility is characterized by the quality and quantity of spermatozoa. Cigarette smoke have potentials to cause oxidative stress, DNA damage, apoptosis and sperm cell. Red dragon fruit’s peel extract acts as an antioxidant against the toxicity of cigarette smokes exposure. Objective: To determine the effect of dragon fruit’s peel extract (Hylocereus polyrhizus) on the quality and quantity of spermatozoa of male white rats (Rattus norvegicus) wistar strains exposed to cigarette smoke. Methods: An experimental study with a post test with control group design. Using 20 white male Wistar rats divided into 5 groups. The positive control group was given smoke exposure of 4 cigarettes, in which the three treatment groups each received an oral gavage of red dragon fruit peel extract at a dose of 350mg;700mg;1400mg. Results: One-way ANOVA test results showed significant differences between groups. The linear regression test showed significant effect on quality and quantity of spermatozoa. Conclusion: Red dragon fruit peel extract (Hylocereus polyrhizus) can increase quality and quantity of spermatozoa of male white rats (Rattus norvegicus) wistar strains exposed to cigarette smoke.