STUDI PENGGUNAAN ANTIBIOTIK GOLONGAN SEFALOSPORIN PADA PASIEN INFEKSI SALURAN KEMIH (Penelitian Dilakukan Di Rumah Sakit Umum Daerah Dr. Saiful Anwar Malang)
Daftar Isi:
- Background : UTI (urinary tract infection) defined as the presence of bacteriuria with a quantitative count ≤ 105 CFU/ml of urine. Nearly 80% of UTI are caused by Escherichia coli. Patients with systemic symptoms requiring hospitalisation should be initially treated with an intravenous antimicrobial regimen, such as aminoglycoside with or without amoxicillin or third generation cephalosporin. Objectives : The aims of the study determine usage patterns of cephalosporin in patients UTI and examine cephalosporin antibiotic therapy related to a given dose, route of administration, duration, and timing of administration are associated with clinical and laboratory data in Dr. Saiful Anwar Malang Hospital. Methods : The research is a retrospective observational study in patients UTI from 1 January to 31 December 2018. Result and Conclusion : The pattern of antibiotic cephalosporin inpatient with UTI that hospitalized in Dr. Saiful Anwar Malang there were 19 patients (73%) who received a single antibiotic and 7 patients (27%) received combinations of antibiotics. The most used pattern of single cephalosporin was Ceftriaxone (2x1g) IV in 10 patients (53%). The most used pattern in combinations of antibiotics was Ceftriaxone (2x1g) IV +Levofloxacin (1x750mg) IV in 2 patients (25%). The most used of cephalosporin switch patterns is a single to single in 4 patients (50%).