FORMULASI SUSU KUDA DENGAN KADAR 15%, 20%, DAN 25% DALAM SEDIAAN GEL CARBOMER 2% SEBAGAI ANTIBAKTERI (Propionibacterium acnes)
Daftar Isi:
- Background: Sumbawa horse milk contains a compound called galactoferrin which has a very good antimicrobial activity. Acne is a skin disease that often occurs at a young or old age. Although not a serious skin disease, but if not treated will cause depression and a crisis of confidence. One of the bacteria that causes acne is Propionibacterium acnes. Objective: This research conducted to determine the effect of horse milk (15%, 20%, and 25% concentration) on a 2% carbomer basis preparations gel toward the physical characteristics (pH, spreadability, viscosity) and on the activity of Propionibacterium acne bacteria. Methods: This research was an experimental research to compare 3 formulas with difference horse milk levels then analyze the physical and chemical characteristics of antibacterial activity. Results and Conclusions: Based on the physical properties test showed it has the same physical characteristics which are soft textured, has the smells typical of horse milk, milky white. Based on the results of the test using the One-way Anova statistic test, the viscosity and spreadability did not have a significant difference in each formula with the value (sig> 0.05). However, the pH test showed that the results were 0.006 which means it has a significant difference because of the values obtained (sig <0.05). Also, the result showed it has no inhibitory power on Propionibacterium acnes bacteria because there is no inhibitory zone produced by formula I, II and III. Suggestion: It is suggested to another researcher to do more research on antibacterial activity test on Sumbawa horse milk.