The Correlation between Pulmonary Function Tests and The Salivary MMP-9 Activity among Chronic Obstructive Pulmonary Disease (COPD) Patients
| Main Authors: | Mulyadi, ., Sunnati, ., Azhary, Mulkan |
|---|---|
| Format: | Article PeerReviewed application/pdf |
| Bahasa: | eng |
| Terbitan: |
Elsevier
, 2016
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| Subjects: | |
| Online Access: |
http://repository.unusa.ac.id/6100/1/The%20Correlation%20between%20Pulmonary%20Function%20Tests%20and%20The%20Salivary%20MMP-9%20Activity%20among%20Chronic%20Obstructive%20Pulmonary%20Disease%20%28COPD%29%20Patients.PDF http://repository.unusa.ac.id/6100/17/peer%20review.pdf http://repository.unusa.ac.id/6100/3/turnitin%20mulyadi.pdf http://repository.unusa.ac.id/6100/ https://www.sciencedirect.com/science/article/pii/S1876619616000310 |
Daftar Isi:
- The spirometry test is routinely performed to assess FEV1, FVC, and FEV1/FVC ratio among chronic obstructive pulmonary disease (COPD) patients with the increased activity of MMP-9. Saliva is less invasive to assess the MMP-9 activity. This study aimed to compare Pulmonary Function Tests to estimate the MMP-9 activity. The respondents were 30 COPD outpatients from Pulmonary Policlinic. Results showed mean ratio of FEV1, FVC, FEV1/FVC (SD) and that of the salivary MMP-9 activity were 1.67 (0.12) L, 2.97 (0.43) L, 56.15 (8.43) % and 1.85 (1.54) μM respectively. The correlation between FEV1, FVC, and FEV1/FVC ratio and the salivary MMP-9 activity was insignificant (p>0.05). The pulmonary function tests were not able to estimate the salivary MMP-9 activity. The findings suggest further activities of MMP-9 from other samples for comparison of protease activity.