The Antidepressant Effects of (Arcangelisia flava (l.) Merr) Water-Soluble Extract in Balb-C Mice Reviewed from Immobility Time by Forced
Main Authors: | A, Tiara, H, Arief R, Sudarsono, Sudarsono |
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Format: | Article info application/pdf eJournal |
Bahasa: | eng |
Terbitan: |
Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity
, 2015
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Subjects: | |
Online Access: |
http://sciencebiology.org/index.php/BIOMEDICH/article/view/22 http://sciencebiology.org/index.php/BIOMEDICH/article/view/22/10 |
Daftar Isi:
- This study was conducted to examine / determine the antidepressant effects of (Arcangelisiaflava L.) on immobility time of the white male mice strain Balb-c by the forced swim test method. The method of research using laboratory animals such as 25 micewas divided into 5 groups. As a negative control group was only given distilled water ad libitum. Amitryptiline was used as the positive control group; the experiment group was a water-soluble extract of A.flava by multiple doses. The results showed that the best antidepressant effects were312 mg/kgBW ; it had a minimum of immobility time compared with the other groups.