Role of Autophagy in Cancer Therapy
| Main Author: | Wargasetia, Teresa Liliana; Faculty of Medicine, Maranatha Christian University, Bandung |
|---|---|
| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2010
|
| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/915 |
Daftar Isi:
- Autophagy is an intracellular degradative system which plays important roles in regulating protein homeostatis and is essential for survival when cells are faced with metabolic stress. Autophagy is one of programmed cell deaths. Studies showed the role of autophagy as a tumor suppressor, but the effect of autophagy in tumor growth and its roles in cancer therapy remain controversial. Further studies are required for application of various autophagy-targeting therapeutic strategies.Keywords: autophagy, cell death, tumor, cancer therapy