Comparison Between Simplified Fencl-Stewart and Figge-Stewart Methods with Henderson-Hasselbach Method in Diagnosis of Metabolic Acidosis
| Main Authors: | Kurnia, Reza; Faculty of Medicine Universitas Padjadjaran/ Dr. Hasan Sadikin General Hospital, Bandung, Alwi, Enny Harliany; Faculty of Medicine Universitas Padjadjaran/ Dr. Hasan Sadikin General Hospital, Bandung, Hilmanto, Dany; Faculty of Medicine Universitas Padjadjaran/ Dr. Hasan Sadikin General Hospital, Bandung |
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| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2010
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| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/750 |
Daftar Isi:
- Assessment of acid-base balance status and diagnosis of metabolic acidosis can be done using the Henderson-Hasselbalch method. The other method is the method of Stewart. The purpose of this study was to compare the methods of a simplified Fencl-Stewart and Figge-Stewart with the Henderson-Hasselbalch method in the diagnosis of metabolic acidosis. This research was conducted in February to May 2010 at the Children Emergency Unit, Pediatric Intensive Care Unit, Pediatric Inpatient Unit, Neurosurgery Intensive Care Unit, and children who consulted from other departments to Child Health Department, Hasan Sadikin Hospital, Bandung . The study was conducted in children aged 1 month-14 years old who required blood gas analysis and in a state of metabolic acidosis based on the Henderson-Hasselbalch method. Blood gases were also analyzed by simplified Fencl-Stewart method and Figge-Stewart method. It was obtained 60 subjects with metabolic acidosis. Of 35 subjects in the Henderson-Hasselbalch method, there is an increasing anion gap to 37 subjects after correction of “excess base the caused by unmeasured anions” (BEua) based on simplified Fencl-Stewart method, and increased to 41 subjects when corrected for albumin factor based on Stewart-Figge method. Analysis using Cohen’s Kappa coefficient of agreement reached 73.3% and 69.6% (p<0.001), stated that the anion gap based on the Henderson-Hasselbalch method equal favorably with a simplified Fencl-Stewart and Figge- Stewart to identify anion that are not measurable. This study concluded the Henderson-Hasselbalch method, a simplified Fencl-Stewart, and Figge-Stewart can be used to identify unmeasured anions in metabolic acidosis.Keywords: Metabolic acidosis, Henderson-Hasselbalch, simplified Fencl-Stewart, Figge-Stewart