Effect of Spinach Juice on Serum NOx Level and Blood Pressure in Young Adult Male
| Main Authors: | Sutadarma, I Wayan Gede; Faculty of Medicine Udayana University, Denpasar, Sayogo, Savitri; Faculty of Medicine University of Indonesia, Jakarta, Effendi, Imam; Faculty of Medicine University of Indonesia, Jakarta |
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| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2010
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| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/718 |
Daftar Isi:
- One of the risk factors of prehypertesion is endothelial dysfunction of the blood vessel. Endothelial dysfunction is caused by decrease of nitric oxide (NO), a condition which could be caused by the low intake of green leafly vegetables. This parallel clinical trial study was conducted to investigate the effect of 100 gram per day spinach for four consecutive weeks on serum NOx and blood pressure in male young adult with normal body weight and blood pressure. A total of 34 subjects who were selected using certain criteria divided into two groups using block randomization. A total of 17 subjects received dietary counseling and 100 gram spinach juice per day for four consecutive weeks (P), while 16 subjects were given only dietary counseling (K). Data collected including age, physical activity, body mass index, intake of energy, sodium, and inorganic nitrate.The assessment of serum nitrate, nitrite, and NOx levels were done in the beginning and the end of the study, while the blood pressure was determined once in every week. Statistical analysis was performed using t and Mann-Whitney test, with the level of significancy was 5%. Inorganic nitrate intake significantly higher in P [130.33 (107.28-195.85) mg/day vs 30.79 (9.47-118.38) mg/day]. Serum nitrate, nitrite, and NOx levels increased in both groups, which higher in P but not significantly different. There was no decreased in terms of blood pressure. This study suggested spinach juice tend to be able to increase serum nirate, nitrite, and NOx levels although has not statistically been proven and also not decreasing the blood pressure.Keywords: young adult male, spinach juice, inorganic nitrate, serum NOx, blood pressure