Goodpasture’s Syndrome in a 12-Year-old Girl with Massive Hemoptysis and Acute Renal Failure
| Main Authors: | Rahayu, Rahayu; Faculty of Medicine Universitas Padjadjaran/ Dr. Hasan Sadikin Hospital, Bandung, Hilmanto, Dany; Faculty of Medicine Universitas Padjadjaran/ Dr. Hasan Sadikin Hospital, Bandung |
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| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2007
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| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/538 |
Daftar Isi:
- Goodpasture’s syndrome is an autoimmune disease composed of progressive glomerulonephritis, pulmonary hemorrhagic, and finding of anti-GBM antibody. Incidence of the disease is about 1:1 000 000; its highest incidence at the age of 20 – 30 years, and sex ratio between male and female is 4:1. A 12-year-old girl was admitted to Hasan Sadikin Hospital with chief complaint of body swelling for 10 days, preceeded with of weakness, fatigue and paleness for 3 weeks, and bloody cough for 4 days. Before admssion to dr Hasan Sadikin Hospital, the patient was admitted to Dr Slamet Hospital in Garut, and received 2 units of blood transfusion. Physical examination renedled palpebra and extremity swelling, hypertension, and anemia without difficulty of breathing. Laboratory findings showed anemia, increased ureum-creatinin high potasium level, proteinuria and hematuria. Chest X-rays showed diffuse infiltrate. The patient was first diagnosed acute renal failure due to acute nephritic syndrome, and was given intravenous furosemide, kayeksalat and packed red cell transfusion. In the emergency unit, she suffered more massive hemoptysis, breathing difficulty and became paler. After 6 hours in the emergency unit, she suffered hypovolemic shock, bradycardia and apnea. After 15 minutes of rescuscitation, the patient died. The patient is final diagnosed was Goodpasture’s syndrome based on the presence of progressive glomerulonephritis and pulmonary hemorrhagic. Even though there was no proof of anti-GBM, clinical features showed description of Goodpasture’s syndrome.Keywords: Goodpasture’s syndrome, glomerulonephritis, pulmonal bleeding, anti-GBM antibody