Plasma Lutein Level in Age-Related Macular Degeneration
| Main Author: | Erry, Erry; Health System and Policy of Research and Development Division Department of Health Republic of Indonesia, Jakarta |
|---|---|
| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2007
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| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/517 |
Daftar Isi:
- The aim of this study is to determine the difference of lutein plasma levels between ARMD and non ARMD, and whether lutein plasma level decreases the risk factor for ARMD. An analytic observational case control study for ARMD patients was done in Cicendo Eye Hospital Bandung, since July 2004 until November 2004. One hundred ninety eight patients, aged 50 to 85 years were included in the case group. Ninety nine patients with ARMD and ninety nine patients without ARMD as a control group. The sample was collected by consecutive admissions, no randomization until the required size of sample was achieved. The lutein plasma level of the two groups was assessed with spectrophotometer. The mean lutein plasma level was 0.148 μmol/l (SD=0.077 μmol/l) for ARMD case group, 0.328 μmol/l (SD=0.313 μmol/l) for non ARMD control group. There was a statistically significant difference between the two groups (t-test=5.561; p<0.0001) with OR=3.83. Risk of ARMD was increased in people with a low plasma level of lutein. The cut off valueof Lutein Concentration this study is <0,15 μmol/L with 66,2% accuracy.Keywords: ARMD, lutein plasma levels, risk factor.