Sepsis in Children: Microbial Pattern and Susceptibility Test
| Main Author: | Dewi, Rismala; Cipto Mangunkusumo General Hospital, Faculty of Medicine University of Indonesia, Jakarta |
|---|---|
| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2011
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| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/338 |
Daftar Isi:
- Sepsis is a disease commonly found in pediatric intensive care unit. Diagnosis of sepsis is established based on clinical manifestation that presents multiple organ failure with the suspicion or confirmation of microorganism finding in blood. Sepsis in children requires comprehensive treatment to improve the prognosis, with antibiotics considered as essential sepsis management. The antimicrobial selection, length and duration of treatment become a challenge because of difficulties in obtaining quick blood culture and susceptibility test results. Thus, antimicrobial treatment should be given merely based on empirical application to prevent drug resistency. The aim of the study is to obtain data on type of pathogenic bacteria responsible for sepsis andits susceptibility to antibacterial agents available. The result would be beneficial as guidance for sepsis management within our unit. The design of the study was cross-sectional. Samples were retrieved between January and October 2010 in pediatric intensive unit at Ciptomangunkusumo Hospital, Jakarta. The subjects were children aged between 1 month to 18 years old. There were 42 subjects fulfilled inclusion criteria, but only 39 samples were analyzed due to the completeness of the data. The most common pathogen is Klebsiella pneumoniae (21%), followed by Serratia marcescens (14%), and Burkolderia cepacia (14%). Antibiotics which are found to be responsive to above pathogens are Cefepime and Levofloxacin.Keywords: sepsis, children, microbacterial, susceptibility test