Recent Developments for Treatment of Atopic Dermatitis
| Main Authors: | Natalia, Natalia; Faculty of Medicine Universitas Indonesia, Jakarta, Menaldi, Sri Linuwih; Faculty of Medicine Universitas Indonesia, Jakarta, Agustin, Triana; Faculty of Medicine Universitas Indonesia, Jakarta |
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| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Journal of the Indonesian Medical Association
, 2011
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| Online Access: |
http://indonesia.digitaljournals.org/index.php/idnmed/article/view/1011 |
Daftar Isi:
- Atopic dermatitis (AD) is a chronically relapsing skin disease that occurs most commonly during early infancy and childhood and may continue on into later life. Atopic dermatitis impact factor in sleep deprivation, lost work days, financial cost, and time taken for skin care concluded. Atopic dermatitis is frequently associated with abnormalities in skin barrier function and allergen sensitization and inherited tendency to incur. This disorder is belived to be related to hypersensitivity, such as asthma and allergic rhinitis. Atopic dermatitis (AD) was eventually added as the cutaneous manifestation of this condition. The diagnosis is based on the constellation of clinical findings by Hanifin and Rajka supported by increased level of IgE and eosinofil as laboratorium findings. The outcome of atopic dermatitis may be difficult to predict and the disease generally tends to be more severe and persistent in young children. Successful treatment of atopic dermatitis requires a systematic, multipronged approach that incorporates skin hydration, pharmacologic therapy, and the identification and elimination of flare factors such as irritants, allergens, infectious agents, and emotional stressors. Treatment should be individualized to address each patient’s skin disease reaction and pattern and the trigger factors that are unique to the particular patient. Atopic dermatitis refractory to conventional forms of therapy, alternative antiinflammatory and immunomodulatory agents may be necessary. Atopic dermatitis creates a significant burden for both families and the community. J Indon Med Assoc. 2011;61:299-304.Keywords: atopic dermatitis, anti-inflammatory, immunomodulatory