Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)
| Main Authors: | Runadi, Dudi, Purnama, Purnama, Salam, Supriatno , Nurlelasari, Nulelasari, Harneti, Desi, Mayanti, Tri , Maharani, Rani , Supratman, Unang, Shiono, Yoshihito |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Institute for Research and Community Services (LPPM) ITB
, 2023
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| Subjects: | |
| Online Access: |
https://journals.itb.ac.id/index.php/jmfs/article/view/19268 https://journals.itb.ac.id/index.php/jmfs/article/view/19268/6204 |
Daftar Isi:
- A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.