The effect of Brotowali (Tinospora crispa (L) Miers ex Hook .f. & Thems ) extracts on Degranulation Mast cell
| Main Authors: | Hainil, Sri, Aldi, Yufri |
|---|---|
| Format: | Article PeerReviewed application/pdf |
| Terbitan: |
RJPBCS Press
, 2016
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| Subjects: | |
| Online Access: |
http://repository.unand.ac.id/23885/1/RJPBCS%207%285%29%20Kedua.pdf http://www.rjpbcs.com/pdf/2016_7(5)/[190].pdf http://repository.unand.ac.id/23885/ |
Daftar Isi:
- Mast cell degranulation that induced by subtance 48/80 at dose of 10 μg/ml from Brotowali extract (Tinospora crispa (L) Miers ex Hook .f. & Thems ) using invitro methode has been investigated. Extract of Brotowali as preparation was maceration using ethanol and fraction of petroleum ether,chloroform and water.The result of study showed that chloroform fraction of Brotowali with concetration of 5 μg/ml to 625 μg/ml inhibited the mast cell degranulation that induced by 10 μg/ml substance 48/80 with significanty (p≤0,01). Keywords: Tinospora crispa (L) Miers ex Hook .f. & Thems; Mast cell degranulation; subtance 48/80; fraction.