UJI FETOTOKSISITAS EKSTRAK DAUN KEMANGI (Ocimum Sanctum L.) PADA MENCIT PUTIH

Main Authors: Almahdy, A, Marina, Yandri
Format: Monograph NonPeerReviewed Book
Bahasa: eng
Terbitan: Farmasi , 2009
Subjects:
Online Access: http://repo.unand.ac.id/1809/1/5._almahdy_fetal_toxic.doc
http://repo.unand.ac.id/1809/
Daftar Isi:
  • The fetotoxicity effect of methanolic extract of the leaf of kemangi (Ocimum Sanctum L.) on mice had been studied. The extract was given orally with variable doses of 50, 100, and 200 mg/kg BW at 6th ¬ until 15th of pregnancy. On the 18th day of pregnancy laparactomy was perpormed on half number of fetuses from each litter. Mice on doses of 500 mg/kg BW caused abortion. Macroscopic observation on the fetuses showed some anomalis of body weight compared to control and there was no malformation accured at all variety of doses.