Hubungan Antara Diabetes Melitus Tipe 2 dengan Retinopati Diabetik Dikaji Dari HbA1c Sebagai Parameter Kontrol Gula Darah
| Main Author: | Rangkuti, Irma Yanti |
|---|---|
| Other Authors: | Harahap, Urip, Parwis, Bebi |
| Format: | Masters |
| Bahasa: | ind |
| Subjects: | |
| Online Access: |
http://repository.usu.ac.id/handle/123456789/26015 |
Daftar Isi:
- Diabetes mellitus (DM) is a metabolic disease characterized by the onset of hyperglycemia due to impaired insulin secretion, and/or improving cellular insulin resistance to insulin. Chronic hyperglycemia and other metabolic disorders DM will cause damage to tissues and organs, such as in the eyes, kidneys, nerves, and vascular system. Diabetic retinopathy is one of complication DM in the eye, sometimes without symptoms, but can cause the blindness and estimated 25 times more patients suffered in DM compared to patients who do not suffer from DM. Monitoring the metabolic status of diabetic patients is important. The method used to determine blood glucose control in all types of DM are glikat measuring hemoglobin (HbA1c). There is also the purpose of this study was to determine the relationship of blood sugar control with diabetic retinopathy in type 2 diabetes with HbA1c as a parameter of blood sugar control, the long-suffering relationship of DM with diabetic retinopathy, and the relationship of age with diabetic retinopathy. This study involved 30 people with type 2 diabetes, by making several measurements and clinical examination and biochemical measurements such as height, weight and waist circumference, blood pressure with a sphygmomanometer Hg and steteskop, blood sugar levels with a spectrophotometer, levels of HbA1c by HPLC technique , sharp vision with a Snellen chart, intra-ocular pressure (IOP) with computerized tonometer, and fundus eye examination with ophthalmoscopy and fundus photos. Patients with more women than men (4:1). Fifteen people (50%) patients with uncontrolled diabetes mellitus and 15 people (50%) patients with uncontrolled DM. Youngest diabetic patient aged 42 years, and the oldest 78 years of age. DM is most experienced at the age between 49-56 years with a number of 6 people (40%) in uncontrolled diabetes mellitus, followed by 5 people (33.33%) in the DM controlled group. DM's most lots have been experienced by patients during 7-12 years as many as 9 people (60%) in group controlled DM, and 8 persons (53.33%) in group DM not controlled. Twenty-three people (76.7%) had no diabetic retinopathy, and 7 persons (23.3%) had diabetic retinopathy. 2 people (6.67%) had uncontrolled diabetes mellitus diabetic retinopathy, and 5 people (16.66%) on uncontrolled diabetes have diabetic retinopathy. Twenty-three people do not experience diabetic retinopathy after suffering from diabetes for a mean 11.22 years, and 7 people experience after suffering from diabetes mellitus diabetic retinopathy during the 16.57-year average. Twenty-three people do not have diabetic retinopathy at an average age of 56.43 years, and 7 people have diabetic retinopathy at an average age of 58.29 years. Based on statistical analysis between control and diabetes mellitus with diabetic retinopathy obtained p = 0.195, this means controlling blood sugar does not cause the occurrence of diabetic retinopathy (p > 0.05). Between long-suffering DM with diabetic retinopathy obtained p = 0.05, this means that the longer suffer the higher risk of developing diabetes mellitus diabetic retinopathy (p < 0.05). Between ages with diabetic retinopathy obtained p = 0.683, this means there is no relationship between age and diabetic retinopathy (p > 0.05).
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