Perbandingan Kadar Immunoglobulin A Sekretori pada Anak Penderita Tonsilitis Kronis Sebelum dan Sesudah Tonsilektomi
| Main Author: | Anggraini, Yulia |
|---|---|
| Other Authors: | Munir, Delfitri, Adenin, Linda I |
| Format: | Masters application/pdf |
| Bahasa: | ind |
| Terbitan: |
Universitas Sumatera Utara
, 2020
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| Subjects: | |
| Online Access: |
http://repositori.usu.ac.id/handle/123456789/25445 |
Daftar Isi:
- 76 Halaman
- PENDAHULUAN: Infeksi pada tonsil merupakan masalah yang paling banyak dijumpai pada populasi anak. Tonsilitis kronik terjadi karena inflamasi yang berulang yang diakibatkan bakteri dan virus. Keluhan yang dijumpai diantaranya sakit ketika menelan, demam, otitis media, sampai obstructive sleep apnea. Hingga saat ini prosedur tonsilektomi masih menjadi kontroversi pada beberapa kalangan dengan pendapat bahwa tonsilektomi dapat menurunkan mekanisme pertahanan tubuh. Tujuan dari penelitian ini adalah untuk mengamati kadar immunoglobulin A sekretori pada pasien tonsillitis anak sebelum dan sesudah tonsilektomi. METODE: Penelitian ini merupakan penelitian analitik komparatif yang membandingkan pasien tonsillitis kronis anak sebelum dan sesudah tonsilektomi. . HASIL: Penelitian ini mendapatkan hasil bahwa kadar immunoglobulin A sekretori pada anak yang sehat adalah 510 ± 802 ng/ml, pada penderita tonsillitis kronis sebelum tonsilektomi 1010 ± 3570 ng/ml, dan sesudah tonsilektomi 580 ± 922 ng/ml. KESIMPULAN: Kadar immunoglobulin A sekretori pada penderita tonsillitis kronis sebelum tonsilektomi tinggi dan 4 minggu setelah tonsilektomi menurun mendekati kadar pada orang normal
- Background : Infection of the tonsils is a fairly common problem in the population especially in children . Chronic tonsillitis happened because of reccuret inflammation in tonsil that caused by bacteria or virus. The complaints among others are pain while swallowing, fever, otitis media, until obstructive sleep apnea. Until now tonsillectomy procedure is still a controversy. Tonsillectomy is a commonly performed surgery in children with chronic tonsillitis. For those against it, tonsillectomy is considered decreasing the body's defense mechanism. The goal of the study is to analyze the secretory immunoglobulin A level on the chronic tonsillitis children patients before and after tonsillectomy. Method: This study was conducted as a comparative analytic study among the chronic tonsillitis children patients before and after tonsillectomy. Result: The result of this study reveals that the level of secretory Ig A in healthy subjects were 510 ± 802 ng/ml, in chronic tonsillitis patients before tonsillectomy were 1010 ± 3570 ng/ml, and after tonsillectomy were 580 ± 922 ng/ml. Conclusion: The level of s-IgA in chronic tonsillitis prior to tonsillectomy was high and 4 weeks post operation the level of s-IgA decreased, close to the level of normal subjects.