COMPREHENSIVE MANAGEMENT OF MUCOUS MEMBRANE PEMPHIGOID IN A MEDICALLY COMPROMISED PATIENT (DIABETES MELLITUS AND HYPERTENSION) (A CASE REPORT)

Main Authors: Sari, Lisa Meutia; Oral Medicine Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Pradono, Siti Aliyah; Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: Faculty of Dentistry, University of Indonesia , 2006
Subjects:
Online Access: http://www.jdentistry.ui.ac.id/index.php/JDI/article/view/267
http://www.jdentistry.ui.ac.id/index.php/JDI/article/view/267/181
Daftar Isi:
  • Mucous membrane pemphigoid (MMP) is an autoimmune mucocutaneous blistering disease characterized by autoantibodies to components within the basement membrane zone. The lesions may produce risk of scarring of the cants (symblepharon), inversion of the eyelashes (entropion) and trauma to the cornea (trichiasis). We reported a case of MMP in a 56-year old female with controlled diabetes mellitus and hypertension whose ocular involvement has lead to blindness of the right eye. The diagnosis of MMP was based on the history and clinical findings in oral medicine department. Management of this patient included the administration of anti-fungal, corticosteroid, diaminodiphenylsulfone, nutritional supplementation oral hygiene promotion and consultation to internal medicine specialist and ophtalmologist. The improvement of oral lesions progressed well within five months. We conclude that optimal improvement can be reached by comprehensive management with controlling systemic factor and good cooperation between medical team and patient.