FORMULASI SEDIAAN SIRUP PENINGKAT IMUNITAS DARI HERBA MENIRAN (Phyllanthus niruri L.)
| Main Authors: | Sugarda, W. O., Dewi, K.D.C., Putra, K.W.A., Yogiswara, M.B., Sukawati, C.B.A.C., Sutresna, P.A.R., Dewi, N.L.G.J., Arisanti, C.I.S., Yustiantara, P.S. |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia
, 2019
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| Online Access: |
https://ojs.unud.ac.id/index.php/jchem/article/view/51705 https://ojs.unud.ac.id/index.php/jchem/article/view/51705/30664 |
Daftar Isi:
- Meniran herb (Phyllanthus niruri L.) is a plant that has been scientifically proven to have activity as a natural immunomodulator. The effectiveness of natural immunomodulators from meniran herbs can be improved by formulating the ethanolic extract of meniran herbs into syrup preparations. This research was conducted to find out that the herbal extracts obtained had fulfilled the parameters of extract quality standards so that they could be formulated into pharmaceutical products. Standardization of herbal extracts includes testing of moisture content, testing of total ash content, testing of acid-soluble ash content, and testing of total flavonoid levels. Ethanol extract of Meniran herbs was obtained by maceration using 95% ethanol. Testing the extract moisture content produced extracts with a moisture content of 7.295%. Total ash content was 3%, acid insoluble ash content was 1.2% and total flavonoid content was 3.15%. Keywords: formulation, immunity, syrup, Phyllanthus niruri L.
- Herba meniran (Phyllanthus niruri L.) merupakan tanaman yang secara ilmiah telah terbukti mempunyai aktivitas sebagai imunomodulator alami. Efektivitas imunomodulator alami dari herba meniran dapat ditingkatkan dengan memformulasikan ekstrak etanol herba meniran menjadi bentuk sediaan sirup. Penelitian ini dilakukan untuk mengetahui bahwa ekstrak herba meniran yang diperoleh telah memenuhi parameter standar mutu ekstrak sehingga dapat diformulasikan menjadi produk farmasi. Standarisasi ekstrak herba meniran meliputi pengujian kadar air, pengujian kadar abu total, pengujian kadar abu larut asam, dan pengujian kadar flavonoid total. Ekstrak etanol herba meniran diperoleh dengan cara maserasi menggunakan etanol 95%. Pengujian kadar air ekstrak menghasilkan ekstrak dengan kadar air sebesar 7,295%. Kadar abu total sebesar 3%, kadar abu tidak larut asam 1,2% dan kadar flavonoid total sebesar 3,15%. Kata kunci: formulasi, imunitas, Phyllanthus niruri L., sirup