Effect Several Soybean (Glycine Max L. Merr) Extracts to Food Intake, Body Weight and Cholecystokinin Plasma in Rats
| Main Authors: | Hidayat, Meilinah, Sujatno, Muchtan, Sutadipura, Nugraha, -, Setiawan |
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| Format: | Proceeding PeerReviewed Book |
| Terbitan: |
, 2009
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| Subjects: | |
| Online Access: |
http://repository.maranatha.edu/1154/1/International%20Symposium%20Seminar_Effect%20Several%20Soybean%20Extracts.pdf http://repository.maranatha.edu/1154/ |
Daftar Isi:
- Several studies have shown that isoflavones and high quality protein in soybean can reduce body weight. Bioactive peptides derived from soybean can stimulate cholecystokinin (CCK) an hormonal regulator of the digestive process which has important role in obesity treatment. The aim of this research was to review which kind of soybean and the fermentation soybean extracts has the highest effects for decreasing food intake, reducing body weight and increasing CCK plasma level in rats. This is a laboratory experimental study using normal Wistar male rats which have completed the inclusion criteria. The material of Local Soybean (Glycine max L. merr Wilis variety) and the high quality Soybean (Glycine max L. merr Detam I variety) were made into tempeh then made into methanol extraction, ethyl acetate fractionation and protein extraction. This research was administered by giving eleven sort of soybean extracts orally to the 13 group of rats for 14 days. Data were analyzed with statistical Analysis of Variance (ANOVA) with Post Hoc Test Duncan an t-test paired after all data was proved as normal distribution by tests of Normality Shapiro-Wilk. The results in this study, Group B which is given methanol extract of local soybean tempeh, Group I which is given protein extract of local soybean tempeh, and Group J which is given protein extract of Soybean Detam I show significant results in all of parameter measurement. The conclusion is methanol extract of local soybean tempeh, protein extract of local soybean tempeh and protein extract of Soybean Detam I give the best result in decreasing food intake, reducing body weight and increasing CCK plasma level in rats.