Anti-hyperuricemia Effect of Water Fraction Cinnamon (Cinnamomum burmannii (Ness & T. Ness) Blume) on White Male Rats
| Main Authors: | Dwitiyanti, Dwitiyanti, Ema, Dewanti, Rizky Arcinthya Rachmania, Rizky |
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| Format: | Article PeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development (MICH-PhD 2018)
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| Subjects: | |
| Online Access: |
http://repository.uhamka.ac.id/810/1/MICH-PhD_2018_18.pdf http://repository.uhamka.ac.id/810/ |
Daftar Isi:
- Hyperuricemia is a condition of increased concentration of uric acid in the blood. Cinnamon bark (Cinnamomum burmannii (Ness & T. Ness) Blume) has been used empirically to decrease uric acid levels. This research is to determine the effect of water fraction from cinnamon bark as anti-hyperuricemia. For being in hyperuricemia condition, the rats were provided with high-purine food and potassium oxonate 50mg/200gBW as an uricase inhibitor. As many as 4,108 mg dose/200gBW of Allopurinol was used as a comparison for positive control. The dose of cinnamon bark used was 104 mg/200g BW for the first group, 208 mg/200g BB for the second group and 416 mg/200gBW for the third group. The result shows that the second group can lower uric acid level (58,87%) and has a similar result with the positive group (P>0.05). It concludes that the water fraction of cinnamon bark has antihyperuricemia effect.