Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil Against Female Winstar Rats

Main Authors: H N Andjani, Andjani, Y Sentosa, Sentosa, YATI, KORI, A Fauzantoro, Fauzantoro, M Gozan, Gozan, Y J Yoo, Yoo
Format: Article PeerReviewed Book
Bahasa: eng
Terbitan: IOP Publishing
Subjects:
Online Access: http://repository.uhamka.ac.id/745/1/Andjani_2019_IOP_Conf._Ser.__Earth_Environ._Sci._353_012047.pdf
http://repository.uhamka.ac.id/745/
Daftar Isi:
  • Tobacco plants are notably known for its pesticidal properties, particularly due to its nicotine content. In this study, Nicotiana tabacum L. bio-oil was obtained using pyrolysis technique. The safety of the bio-oil to be used as bioinsecticide was analyzed through acute oral toxicity test by administering 5000 mg bio-oil/kg body weight of female winstar rats that were analogous to humans. It was concluded that the bio-oil was not toxic due to absence of mortality and no significant change in the body weight and behavior of the rats.