The use of selected biomarkers, phagocytic and cholinesterase activity to detect the effect of dimethoate on marine mussel (Mytillus edulis)

Main Authors: Yaqin, Khusnul, Lay, Bibiana Widiati, Riani, Etty, Masud, Zainal Alim, Hansen, Peter-Diedrich
Terbitan: IPB (Bogor Agricultural University) , 2011
Online Access: http://repository.ipb.ac.id/handle/123456789/42822
Daftar Isi:
  • Effects of organophosphorous pesticide, dimethoate on blue mussels, Mytilus edulis using selected biomarkers have been studied. Mussels were exposed to serial dilutions of dimethoate, 7.88, 15.75, 31.35, and 63.00 μg/l including positive and negative controls for 14 days. The suppression effects of dimethoate on phagocytic activity significantly occurred at two lowest concentrations of dimethoate (7.88 and 15.75 μg/l), but stimulation effects significantly emerged at the following highest concentrations (31.35 and 63.00 μg/l). The declining tendency of the cholinesterase (ChE) activity (23% lower than the control) appeared when mussels exposed to 7.88 and 15.75 μg/l dimethoate. Moreover, the significant inhibition of the ChE activity occurred at 31.35 μg/l dimethoate exposure. This study suggested that the phagocytic and the ChE activity are useful biomarkers for assessing the affects of organophosporous pesticide, dimethoate on neuro-immune system of blue mussels, M. edulis.