Fifty Percent Of Food Restriction During Gestation Reduced The Dendritic Density Of Cerebrum And Cerebellum Of Rattus Norvegicus’ Newborn
| Main Authors: | Anwar Fauzi, Widjiati, Hermanto Tri Joewono |
|---|---|
| Format: | Article PeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
Department Obstetrics & Gynecology, Faculty of Medicine, Universitas Airlangga
, 2018
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/99252/1/2.%203.%20Fifty%20percent%20of%20food%20restriction%20during%20gestation%20reduced%20the%20dendritic%20density%20of%20cerebrum%20and%20cerebellum%20of%20Rattus%20novergicus%20newborn.pdf http://repository.unair.ac.id/99252/2/Fifty%20Percent%20of%20Food%20Restriction.pdf http://repository.unair.ac.id/99252/3/Fifty%20percent%20of%20food%20restriction%20during%20gestation%20reduced%20the%20dendritic%20density%20of%20cerebrum%20and%20cerebellum%20of%20Rattus%20novergicus%20newborn.pdf http://repository.unair.ac.id/99252/ https://e-journal.unair.ac.id/MOG/article/view/10737 http://dx.doi.org/10.20473/mog.V26I32018.112-117 |
Daftar Isi:
- Objectives: To analyze the influence of 50 percent food restriction during pregnancy to the dendritic density of cerebellum and cerebellum of newborn Rattus norvegicus. Materials and Methods: Laboratory experimental study with single blind randomized post-test only control group design using animal model; pregnant Rattus norvegicus as treatment models. Subjects were divided into two groups: control group and treatment group which was exposed to 50% food restriction (FR 50%). At day 21, both group sacrificed and the cerebrum and cerebelum of the offsprings were prepared and stained with silver impregnation. We used parametric independent t-test in analyzing dendritic density. Results: In the cerebrum there was a significant difference in dendritic density between control (4.98+2.17) and treatment (2.69+0.76) groups with p=0.001 (p<0.05). In the cerebellum there was ALSO a significant difference in dendritic density between control (7.37+2.23) and treatment groups (3.01+0.64) with p=0.000 (p<0.05). Conclusions: The dendritic density of cerebrum and cerebellum of newborn Rattus norvegicusexposed to 50 percent of food restriction during pregnancy were lower than control.