Valsartan (Profiles of Drugs Substances, Excipients and Related Methodology)
Main Authors: | Febri Ardiana, Suciati, Gunawan Indrayanto |
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Other Authors: | Harry G. Brittain |
Format: | BookSection PeerReviewed Book |
Bahasa: | eng |
Terbitan: |
Elsevier Academic Press
, 2015
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Subjects: | |
Online Access: |
http://repository.unair.ac.id/93642/1/C-04%20Artikel.pdf http://repository.unair.ac.id/93642/3/C-04%20Reviewer.pdf http://repository.unair.ac.id/93642/4/C-04%20Result.pdf http://repository.unair.ac.id/93642/ https://www.sciencedirect.com/science/article/pii/S1871512515000059?via%3Dihub |
Daftar Isi:
- Valsartan is an antihypertensive drug which selectively inhibits angiotensin receptor type II. This tetrazole derivative was first developed by Novartis and marketed under brand name Diovan® . This compound is orally active and is rapidly absorbed after oral doses, having a bioavailability of approximately 23% . Valsartan appears as a white or almost white hygroscopic powder. This compound must be kept in an air-tight container and should be protected from light and heat. It is available in film-coated tablets containing valsartan 40, 80, 160, or 320 mg, and capsules with dosage of 80 or 160 mg. Tablet combinations of valsartan with hydrochlorothiazide or amlodipine are also available