Aktivitas Alkaloid Daun Jarong (Achyranthes aspera Linn) Terhadap Kematian Sel Kanker Mammae (Mus musculus)

Main Authors: Rahma Putri Anggraini, Dewa Ketut Meles, Eka Pramyrtha Hestianah, Wurlina
Format: Article PeerReviewed Book
Bahasa: ind
Terbitan: Fakultas Kedokteran Hewan Universitas Airlangga , 2017
Subjects:
Online Access: http://repository.unair.ac.id/92425/1/Bukti%2019.%20Aktivitas%20Alkoid%20Daun%20Jarong%20......pdf
http://repository.unair.ac.id/92425/2/Peer%20Review%20Bukti%20C19_compressed.pdf
http://repository.unair.ac.id/92425/
ctrlnum 92425
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><relation>http://repository.unair.ac.id/92425/</relation><title>Aktivitas Alkaloid Daun Jarong (Achyranthes aspera Linn) Terhadap Kematian Sel Kanker Mammae (Mus musculus)</title><creator>Rahma Putri Anggraini</creator><creator>Dewa Ketut Meles</creator><creator>Eka Pramyrtha Hestianah</creator><creator>Wurlina</creator><subject>SF811-909 Veterinary medicine of special organs, regions, and systems</subject><description>The purpose of this study was to describe activity of alkaloid of jarong leaves (Achyranthes aspera Linn ) on the death of cancer cells in the breasts cancer of mice (Mus musculus). Twenty four mice were divided into six treatment groups which each group consists of four mice, K- as control were induced CMC Na 0,5%, meanwhile K+, P0, P1, P2, and P3 were induced with Benzo[a]pyrene, and then given alkaloid of jarong leaves (Achyranthes aspera Linn ) and metotreksat for positive control. Sacrified and staining at weeks as seventeen and eighteen. The data of apoptosis and necrosis breast cancer cells was analyzed using One wayAnova test and continued by Honestly Significant Difference test. The result of this study showed there were significant (p&lt;0,05), but between positive control and P1,P2,P3 given same effect in apoptosis and necrosis incident of breast cancer death. The present study shows that alkaloid of jarong leaves (Achyranthes aspera Linn) has a therapeutic dose almost similar to metotreksat. &#xD; &#xD; Keywords : Alkaloid, Achyranthes aspera Linn, breast cancer, mice</description><publisher>Fakultas Kedokteran Hewan Universitas Airlangga</publisher><date>2017-07</date><type>Journal:Article</type><type>PeerReview:PeerReviewed</type><type>Book:Book</type><language>ind</language><identifier>http://repository.unair.ac.id/92425/1/Bukti%2019.%20Aktivitas%20Alkoid%20Daun%20Jarong%20......pdf</identifier><type>Book:Book</type><language>ind</language><identifier>http://repository.unair.ac.id/92425/2/Peer%20Review%20Bukti%20C19_compressed.pdf</identifier><identifier> Rahma Putri Anggraini and Dewa Ketut Meles and Eka Pramyrtha Hestianah and Wurlina (2017) Aktivitas Alkaloid Daun Jarong (Achyranthes aspera Linn) Terhadap Kematian Sel Kanker Mammae (Mus musculus). Veterinaria Medika, 10 (2). pp. 159-165. ISSN 1979-1305 </identifier><recordID>92425</recordID></dc>
language ind
format Journal:Article
Journal
PeerReview:PeerReviewed
PeerReview
Book:Book
Book
author Rahma Putri Anggraini
Dewa Ketut Meles
Eka Pramyrtha Hestianah
Wurlina
title Aktivitas Alkaloid Daun Jarong (Achyranthes aspera Linn) Terhadap Kematian Sel Kanker Mammae (Mus musculus)
publisher Fakultas Kedokteran Hewan Universitas Airlangga
publishDate 2017
topic SF811-909 Veterinary medicine of special organs
regions
and systems
url http://repository.unair.ac.id/92425/1/Bukti%2019.%20Aktivitas%20Alkoid%20Daun%20Jarong%20......pdf
http://repository.unair.ac.id/92425/2/Peer%20Review%20Bukti%20C19_compressed.pdf
http://repository.unair.ac.id/92425/
contents The purpose of this study was to describe activity of alkaloid of jarong leaves (Achyranthes aspera Linn ) on the death of cancer cells in the breasts cancer of mice (Mus musculus). Twenty four mice were divided into six treatment groups which each group consists of four mice, K- as control were induced CMC Na 0,5%, meanwhile K+, P0, P1, P2, and P3 were induced with Benzo[a]pyrene, and then given alkaloid of jarong leaves (Achyranthes aspera Linn ) and metotreksat for positive control. Sacrified and staining at weeks as seventeen and eighteen. The data of apoptosis and necrosis breast cancer cells was analyzed using One wayAnova test and continued by Honestly Significant Difference test. The result of this study showed there were significant (p<0,05), but between positive control and P1,P2,P3 given same effect in apoptosis and necrosis incident of breast cancer death. The present study shows that alkaloid of jarong leaves (Achyranthes aspera Linn) has a therapeutic dose almost similar to metotreksat. Keywords : Alkaloid, Achyranthes aspera Linn, breast cancer, mice
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