ANALISIS SEKUENS REGIO ENTEROTOKSIN GEN NSP4 DAN GENOTIPE ROTAVIRUS BERDASARKAN GEN NSP4 DAN VP4 PADA ANAK DENGAN DERAJAT KEPARAHAN DIARE AKUT DI BANDAR LAMPUNG TAHUN 2016 DAN 2018
| Main Author: | ELSA FITRI ANA, NIM011617017349 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/92038/1/abstrak.pdf http://repository.unair.ac.id/92038/2/daftar%20isi.pdf http://repository.unair.ac.id/92038/3/daftar%20pustaka.pdf http://repository.unair.ac.id/92038/4/full%20text.pdf http://repository.unair.ac.id/92038/ |
Daftar Isi:
- Rotavirus is the most common cause of diarrhea in children under 5 years old. Rotavirus has 11 genes coding 11 proteins. the NSP4 protein binds to VP4 protein during morphogenesis at amino acids 112–148. The protein interactions during morphogenesis influence rotavirus gene constellation. NSP4 protein is the first viral enterotoxin protein. Changes in amino acids from the enterotoxin region are likely to be related to rotavirus pathogenesis variations. Information on NSP4 and VP4 genetic variations and changes in amino acid sequences within the enterotoxin region of NSP4 gene is still limited in Indonesia, especially in Lampung.