PENGARUH KONSENTRASI POLIMER TERHADAP DRUG DEPOSITION MIKROSFER CIPROFLOXACIN HCl- KARAGENAN DI PARU TIKUS
| Main Author: | CINDY ALICIA ESTHERLINE, 051511133139 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/90660/1/FF.F.30-19%20Est%20p%20abstrak.pdf http://repository.unair.ac.id/90660/2/FF.F.30-19%20Est%20p%20daftar%20isi.pdf http://repository.unair.ac.id/90660/3/FF.F.30-19%20Est%20p%20daftar%20pustaka.pdf http://repository.unair.ac.id/90660/4/FF.F.30-19%20Est%20p.pdf http://repository.unair.ac.id/90660/ http://lib.unair.ac.id |
Daftar Isi:
- The aim of this research was to investigate drug deposition of ciprofloxacin HCl using carageenanmicrosphere as polymer matrix. Microspheres waere administered to rat using nose-only exposure method as rat is know as nose only-breathing animal. Drug deposition in rat lungs was observed using fluorescence microscope and Rhodamine B as fluorochrome. The result showed that the microspheres system was able to get ciprofloxacin to the target site and the increase in polymer concentration prolong the drug residence time in lung.