MANFAAT PEMBERIAN MADU LEBAH (Apis dorsata) UNTUK MENCEGAH OSTEOPOROSIS BERDASARKAN PERLUASAN LAKUNA TULANG VERTEBRAE LUMBALIS TIKUS PUTIH (Rattus norvegicus) SETELAH OVARIOHISTEREKTOMI
| Main Author: | SAMSI YORDAN, 061511133171 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/83982/1/KH%2071-19%20Yor%20m-%20-%20ABSTRAK.pdf http://repository.unair.ac.id/83982/2/KH%2071-19%20Yor%20m-%20-%20DAFTAR%20ISI.pdf http://repository.unair.ac.id/83982/3/KH%2071-19%20Yor%20m-%20-%20DAFTAR%20PUSTAKA.pdf http://repository.unair.ac.id/83982/4/KH%2071-19%20Yor%20m-%20-%20FULLTEXT.pdf http://repository.unair.ac.id/83982/ http://lib.unair.ac.id |
Daftar Isi:
- The aim of this research was to determine the potential of honey bee (Apis dorsata) in preventing osteoporosis based on the expansion of lacuna vertebrae of white rat (Rattus norvegicus) after ovariohysterectomy. The samples were 20 female rats adapted for 7 days in cluster cage and divided randomly into 5 groups (SO, OH, M1, M2, M3). SO was a sham operated groups which non ovariohysterectomized rats that received aquadest. OH is an ovariohysterectomized groups which is the rats were ovariohysterectomized and received aquadest. M1 (1 g/kgBW), M2 (2 g/kgBW) and M3 (4 g/kgBW) were ovarohysterectomized rats and received honey solutions of Apis dorsata. Honey be diluted in 1 ml aquadest and given orally for 84 days. On the 85th day rats were euthanized and vertebrae lumbar was taken with necroption technique. Lacuna area and scoring percentage of expansion were measured using optilab microscope. The result show there was significant difference (p<0.05) on Lakuna area and scoring percentage between OH group and all of the groups. The result of the highest scoring percentage are on M2 group and the lowest are on OH group. The result of the lowest lakuna area are on M2 group and the highest are on OH group.