UJI DAYA HAMBAT EKSTRAK ETANOL KAYU SECANG (Caesalpinia sappan L.) TERHADAP PERTUMBUHAN JAMUR Microsporum canis SECARA IN VITRO
| Main Author: | SURYANINGRUM, 061511535029 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | ind |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/82516/1/PSDKU.KH.%2013%20-19%20Sur%20u%20Abstrak.pdf http://repository.unair.ac.id/82516/2/PSDKU.KH.%2013%20-19%20Sur%20u.pdf http://repository.unair.ac.id/82516/ http://lib.unair.ac.id |
Daftar Isi:
- Dermatophytosis currently characterized a skin disease that frequently infect pets such as dogs and cats. Dermatophytosis is a zoonotic disease, one of the causes of dermatophytosis is Microsporum canis. Secang wood (Caesalpinia sappan L.) is herbal medicine that contains antimicrobial compounds, wich know as flavonoid; phenol; brazilin; homoisoflavonoid; xanthone; saponin. The aim of this research was to study the antifungal activity ethanol extract of secang wood (Caesalpinia sappan L.) on fungal growth inhibition of Microsporum canis using diffuse disc method. The result of the inhibition zone was analyzed using ANOVA (Analysis of Variance) test and continued using Duncan test showed significantly different among the treatments (p <0.05). The inhibition number of positive control used ketoconazole 2% was 12,97c ± 0,42, and the negative control used CMC Na 0,5% was 0,00a ± 0,00. The result of concentration 1 used ethanol extract of secang wood 20% was 0,00a ± 0,00; concentration 2 used ethanol extract of secang wood 40% 8,87bc ± 0,51; concentration 3 used ethanol extract of secang wood 60% 10,95bc ± 0,58; concentration 4 used ethanol extract of secang wood 80% 6,55b ± 5,72; concentration 5 used ethanol extract of secang wood 100% 5,75b ± 5,02. It showed that ethanol extract of secang wood (Caesalpinia sappan L.) have antifungal activity to against Microsporum canis growth with 40% of Minimal Inhibitory Concentration (MIC).