SINTESIS DAN KARAKTERISASI CARBON DOTS BERBAHAN DASAR ASAM ASKORBAT SEBAGAI KANDIDAT PENANDA BIOLOGIS KANKER
| Main Author: | SAYYIDATI ARISTIFANNIY ROHIM, 091615053001 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | ind |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/82055/1/TT.%2005-19%20Roh%20s%20Abstrak.pdf http://repository.unair.ac.id/82055/2/TT.%2005-19%20Roh%20s.pdf http://repository.unair.ac.id/82055/ http://lib.unair.ac.id |
Daftar Isi:
- This study aimed to synthesize and characterize of carbon dots (CDs) originating from ascorbic acid as biomedical applications. This material could be used for a cancer biomarker. The synthesis used microwave radiation as heating source with time variations. The results showed that the best sample had ± 2 nm and the highest fluorescence intensity which was microwave-irradiated for 3.30 minutes. This sample was conjugated with folic acid (FA) which had functional groups that indicated CDs and folic acid. The result of the cytotoxicity test showed non-toxic doses were 0.6 μM CDs; 0.6 and 6 μM CDs – FA. The best dose was used to cell targeting imaging to bladder cancer cell – line. The explanations about characterizations would be discussed on discussion chapter.