EFEK PEMBERIAN EKSTRAK DAUN JUWET (Syzygium cumini) SEBAGAI TERAPI ADJUVANT TERHADAP GAMBARAN HISTOPATOLOGI PARU-PARU MENCIT (Mus musculus) YANG DIINFEKSI Plasmodium berghei
| Main Author: | Ridhofajuri Winanda, 061411133056 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/78339/1/abstrak%20kkc%20kk%20kh%20251-18%20win%20e-min.pdf http://repository.unair.ac.id/78339/2/kkc%20kk%20kh%20251-18%20win%20e-min.pdf http://repository.unair.ac.id/78339/ http://lib.unair.ac.id |
Daftar Isi:
- This research aims to understand the effect of juwet leave extract as adjuvant treatment in edema lung damage, hemmorhagy, alveolar congestion, and thickening of alveolar septa in mouse (Mus musculus) is infected by Plasmodium berghei. Twenty five mouses are divided into five mouses for three control groups which are K0, K1, K2 infected by Plasmodium berghei as 1x106 in 0,2 ml. Then, ten mouses for two treatment groups which are P1 and P2 that are infected by Plasmodium berghei 1x106 in 0.2 ml. The data is analyzed by using Kruskal Wallis Test. If there is a significant change ( p<0.05 ) then it will be continued by using Mann-Whitney Test to compare every effect of each treatment. The statistic analysis in this research uses SPSS program (Statistical Program of Social Science). The result of the statistical analysis showed significant differences on edema lung damage, hemmorhagy, alveolar congestion, and thickening of alveolar septa of group K1 and P2, but there is no significant differences on edema lung damage, hemmorhagy, alveolar congestion, and thickening of alveolar septa of group K2 and P1. The increase of edema lung damage, hemmorhagy, alveolar congestion, and thickening of alveolar septa can be seen from K1 infected by Plasmodium berghei without treatment. The decrease of edema lung damage, hemmorhagy, alveolar congestion, and thickening of alveolar septa of P2 infected by Plasmodium berghei with chloroquine treatment and juwet leave extract. There is no significant difference in edema lung damage, hemmorhagy, alveolar congestion, and thickening of alveolar septa between K2 infected by Plasmodium berghei with chloroquine treatment and P1 infected by Plasmodium berghei with juwet leave extract treatment.