Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
| Main Authors: | Tanjung, Mulyadi, Saputri, Ratih Dewi, Fitriati, Faiz Fakhriah, Tjahjandarie, Tjitjik Srie |
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| Format: | Article PeerReviewed Image Book |
| Bahasa: | eng |
| Terbitan: |
Har Krishan Bhalla & Sons
, 2016
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/63045/1/Cover.pdf http://repository.unair.ac.id/63045/2/Bukti%20C15.%20Antimalarial%20and%20Antioxidant%20Activities%20of%20Isoprenylated%20..........pdf http://repository.unair.ac.id/63045/3/Bukti%20C15%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf http://repository.unair.ac.id/63045/ http://dx.doi.org/10.1080/22311866.2016.1188726 |
Daftar Isi:
- The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate extracts, as well as compounds 1-3 were evaluated for their antimalarial activity against Plasmodium falciparum strain 3D7 (chloroquine-sensitive) and their antioxidant activity against DPPH radical scavenging. Compound 2 exhibited slightly more active than chloroquine. Compounds 1 and 3 showed very high activity against DPPH radical.