The Influence of Sodium Fluoride on the Growth of Ameloblasts and Kidney Proximal Tubular Cells
| Main Authors: | Waluyo, Soegeng, ISMIYATIN, K, PURWANTO, B, MUKONO, I.S |
|---|---|
| Format: | Article PeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2017
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/61447/1/Peer%20Reviewer%20SG%202.pdf http://repository.unair.ac.id/61447/2/fb2017a0006.pdf http://repository.unair.ac.id/61447/ |
Daftar Isi:
- Abstract. Fluoride has toxic potential particularly for teeth, bones, and kidney. This study was aimed to in- vestigate the NaF exposure effects on the growth of ameloblasts and kidney proximal tubular cells. Adult male healthy rats were used as experiment models, divided into control and NaF-induced groups. The expression of amelogenin, Bcl-2, and caspase-3 were significantly different in the control and NaF-induced group (P < 0.05). There was no correlation among these proteins in the control group but significant correlation in the NaF-induced group (r = 0.694). There was a significant correlation in proximal tubu - lar cells, as seen from the increase of caspase-3 in the NaF-induced group (r = 0.715).