EFEK HEPATOPROTEKTOR EKSTRAK BIT MERAH (Beta vulgaris L.) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT (Mus musculus) YANG DIPAPAR Pb
| Main Author: | AISYAH SHAUMANUR ARTHA HIDAYAH, 061211133053 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2016
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/60495/1/ABSTRACT%20KKC%20KK%20KH.%2096.17%20Hid%20e.pdf http://repository.unair.ac.id/60495/2/FULLTEXT%20KKC%20KK%20KH.%2096.17%20Hid%20e.pdf http://repository.unair.ac.id/60495/ http://lib.unair.ac.id |
Daftar Isi:
- The purpose of this study was to know hepatoprotector potential of red beet (Beta vulgaris L) extract in lead induced mice. The research has been done on July, 2th 2015-August, 19th 2015 at Department of Veterinary Pathology, Faculty of Veterinary Medicine, Airlangga University. Twenty five male mice (Mus muculus) aged 60-90 days with BW 27-32 g were used. These animals were divided into five groups (K-, K+, P1, P2, and P3). K- were treated with CMC Na 0,5% 0,1 ml/bw/days, K+ were treated with lead 20 mg/bw/day, P1 were treated with extract of red beet 200 mg/bw/day and lead 20 mg/bw/day, P2 were treated with extract of red beet 400 mg/bw/day and lead 20 mg/bw/day, and P3 were treated with extract of red beet 800 mg/bw/day and lead 20 mg/bw/day. This research has been conducted for 27 days to determine the toxic effects of lead on the liver. The data were analyzed using Kruskal-Wallis test and Post Hoc test. Which performed with SPSS v20.0 for windows. The result showed there were significant (p<0,05) different between treatment groups, which is all dosage treatment had been proved have potential to protect on hepatosit. In conclusion, the research demonstrated that histopathological changes due to lead-induced (20 mg/kgBW) could be treated effectively of red beet extract on the target organ.