ASOSIASI POSITIVITAS NONTUBERCULOUS MYCOBACTERIA DENGAN DERAJAT KEPARAHAN PASIEN TUBERKULOSIS PARU
| Main Author: | Deby Kusumaningrum, 011228226304 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | ind |
| Terbitan: |
, 2015
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/57052/1/TMBK.%2003-16%20Kus%20a%20abstrak.pdf http://repository.unair.ac.id/57052/2/TMBK.%2003-16%20Kus%20a%20bab.pdf http://repository.unair.ac.id/57052/3/TMBK.%2003-16%20Kus%20a%20lampiran.pdf http://repository.unair.ac.id/57052/ http://lib.unair.ac.id |
Daftar Isi:
- Purpose:The research aims to detect a positive association betweenNon tuberculous Mycobacteria and the severity of pulmonary Tuberculosis patients and to find out what spesies of NTM is detected in patients with pulmonary TB. Method: This study was conducted 40 isolat Mycobacteria at laboratory Clinical Microbiology Soetomo Hospital from patient TB .Colonies were then examined using immunochromatographic antigen MPT 64, then a molecular test was performed using PCR and sequencing. Result: The result showed from 40 samples were used, 20 isolatwere NTM and 20 M.tuberculosis complex. Sequencing of 20 samples were positive by PCR 116SrRNA, and detected Mycobacterium kansasii (30%), Mycobacterium gordonae (5%), Mycobacterium parascrofulaceum (2,5%), Mycobacterium simiae (2,5%) Mycobacterium avium (2,5%), Mycobacterium terrae(2,5%). Clinical severity by Bandim TB score from patients medical record showed asignificant assosiation between positivity of NTM detection and the severity among Tuberculosis patients , with p value =0,03. Conclusion:This finding suggest that NTM infection detection is associated with disease severity of pulmonary TB.. Key word: Nontuberculous Mycobacteria, Severity Class, Tuberculosis