HUBUNGAN ANTARA EKSPRESI INTERLEUKIN 17 DENGAN DESTRUKSI TULANG PADA OTITIS MEDIA SUPURATIF KRONIK TANPA KOLESTEATOMA

Main Author: Faizal Rachman, 011080501
Format: Thesis NonPeerReviewed Book
Bahasa: eng
Terbitan: , 2016
Subjects:
Online Access: http://repository.unair.ac.id/55825/1/ABSTRACT.pdf
http://repository.unair.ac.id/55825/2/PPDS.%20THT.%2005-16%20Rac%20h.pdf
http://repository.unair.ac.id/55825/
http://lib.unair.ac.id
ctrlnum 55825
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><relation>http://repository.unair.ac.id/55825/</relation><title>HUBUNGAN ANTARA EKSPRESI INTERLEUKIN 17 DENGAN DESTRUKSI TULANG PADA OTITIS MEDIA SUPURATIF KRONIK TANPA KOLESTEATOMA</title><creator>Faizal Rachman, 011080501</creator><subject>RF Otorhinolaryngology</subject><description>Objective : to explain the correlation between IL-17 expression in granulation tissue with bone erosion in chronic suppurative otitis media (CSOM) witout cholesteatoma&#xD; Design of study : cross sectional&#xD; Method : We performed prospective collection of granulation tissue during mastoidectomy from CSOM without cholesteatoma patient. The tissue samples divided into two groups, with and without bone erosion. All tissues group processed for all samples were then IL-17 examined with mouse monoclonal antibody anti human IL-17 stated in Intensity Distribution Score (IDS). The expression of IL-17 categorized strong intensity, moderate intensity, weak intensity and negative. Strong intensity if IDS about 276.00 &#x2013; 300, moderate intensity if IDS about 151.00 &#x2013; 275.99, weak intensity if IDS about 76.00 &#x2013; 150.99 and IL-17 negative if IDS about 0-76.99. Result : There were 18 samples, 4 with bone erosion and 14 without bone erosion. Expression of IL-17 in the granulation tissue with bone erosion obtained IL-17 moderate intensity were as many as 3 (75%) tissues and IL-17 weak intensity were as many as 1 (25%) tissues. Expression of IL-17 in the granulation tissue without bone erosion obtained IL-17 negative were as many as 6 (42,86%) tissues and IL-17 weak intensity were as many as 8 (57,14%) tissues. Statistical analysis using the Mann-Whitney test p value = 0.005. That means there were significant correlation between IL-17 expression and bone erosion in CSOM without cholesteatoma patients (p &lt; 0.05).&#xD; Conclusion : there were correlation between IL-17 expression and bone erosion in CSOM without cholesteatoma patients in CSOM patients</description><date>2016</date><type>Thesis:Thesis</type><type>PeerReview:NonPeerReviewed</type><type>Book:Book</type><language>eng</language><identifier>http://repository.unair.ac.id/55825/1/ABSTRACT.pdf</identifier><type>Book:Book</type><language>ind</language><identifier>http://repository.unair.ac.id/55825/2/PPDS.%20THT.%2005-16%20Rac%20h.pdf</identifier><identifier> Faizal Rachman, 011080501 (2016) HUBUNGAN ANTARA EKSPRESI INTERLEUKIN 17 DENGAN DESTRUKSI TULANG PADA OTITIS MEDIA SUPURATIF KRONIK TANPA KOLESTEATOMA. Thesis thesis, Universitas Airlangga. </identifier><relation>http://lib.unair.ac.id</relation><recordID>55825</recordID></dc>
language eng
format Thesis:Thesis
Thesis
PeerReview:NonPeerReviewed
PeerReview
Book:Book
Book
author Faizal Rachman, 011080501
title HUBUNGAN ANTARA EKSPRESI INTERLEUKIN 17 DENGAN DESTRUKSI TULANG PADA OTITIS MEDIA SUPURATIF KRONIK TANPA KOLESTEATOMA
publishDate 2016
topic RF Otorhinolaryngology
url http://repository.unair.ac.id/55825/1/ABSTRACT.pdf
http://repository.unair.ac.id/55825/2/PPDS.%20THT.%2005-16%20Rac%20h.pdf
http://repository.unair.ac.id/55825/
http://lib.unair.ac.id
contents Objective : to explain the correlation between IL-17 expression in granulation tissue with bone erosion in chronic suppurative otitis media (CSOM) witout cholesteatoma Design of study : cross sectional Method : We performed prospective collection of granulation tissue during mastoidectomy from CSOM without cholesteatoma patient. The tissue samples divided into two groups, with and without bone erosion. All tissues group processed for all samples were then IL-17 examined with mouse monoclonal antibody anti human IL-17 stated in Intensity Distribution Score (IDS). The expression of IL-17 categorized strong intensity, moderate intensity, weak intensity and negative. Strong intensity if IDS about 276.00 – 300, moderate intensity if IDS about 151.00 – 275.99, weak intensity if IDS about 76.00 – 150.99 and IL-17 negative if IDS about 0-76.99. Result : There were 18 samples, 4 with bone erosion and 14 without bone erosion. Expression of IL-17 in the granulation tissue with bone erosion obtained IL-17 moderate intensity were as many as 3 (75%) tissues and IL-17 weak intensity were as many as 1 (25%) tissues. Expression of IL-17 in the granulation tissue without bone erosion obtained IL-17 negative were as many as 6 (42,86%) tissues and IL-17 weak intensity were as many as 8 (57,14%) tissues. Statistical analysis using the Mann-Whitney test p value = 0.005. That means there were significant correlation between IL-17 expression and bone erosion in CSOM without cholesteatoma patients (p < 0.05). Conclusion : there were correlation between IL-17 expression and bone erosion in CSOM without cholesteatoma patients in CSOM patients
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