PENGARUH ASAM 4-HIDROKSISINAMAT DAN ASAM 4-METOKSISINAMAT TERHADAP AKTIVITAS TIROSINASE
| Main Author: | SEPTIANA, 059912172 |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | ind |
| Terbitan: |
, 2004
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/55732/1/FF%20102.04%20SEP%20P%282003%29.pdf http://repository.unair.ac.id/55732/ http://lib.unair.ac.id |
Daftar Isi:
- Tyrosinase is known to be a key enzyme for melanin biosynthesis. Therefore, inhibition in tyrosinase activity will cause a decreasing in melanin production. The inhibition of cinnamic acid and its derivatives against tyrosinase has been studied as the effort to find a new effective skin-lightening agent. 4hidroxycinnamic acid and 4-metoxicinamic acid as two of cinnamic acid derivatives was tested to know its effect on inhibiting tyrosinase. To Asses the efficacy of tyrosinase inhibition, tyrosinase activity using LTyrosine as a substrate was assayed spectrofotometrically with the dopachrome method. Michaelis-Menten constant (Km) and maximum velocity (Vmax) of the enzyme activity were showed by Lineweavar-Burk's plots.