Biomarker of Bipolar Disorder
| Main Author: | Maria Maramis, Margarita |
|---|---|
| Other Authors: | Konginan, Agustina, Rachma, Frilya, Sajogo, Ivana |
| Format: | BookSection PeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
Departemen Ilmu Kedokteran Jiwa Fakultas Kedokteran Unair
, 2015
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| Subjects: | |
| Online Access: |
http://repository.unair.ac.id/55003/1/karil%2014.%20Biomarker%20of%20Bipolar%20Disorder.pdf http://repository.unair.ac.id/55003/2/peerreview14.Biomarker%20of%20Bipolar.pdf http://repository.unair.ac.id/55003/ |
Daftar Isi:
- Bipolar disorder is a medical illness characterized by recurrent episodes of mania or hypomania and major depression. Present in all cultures and races with a similar prevalence of 1.6%. Studies that considered all the range of bipolor spectrum, report a lifetime prevalence fiuctuating between 3.7 % and 6 %. Despite its debilitating symptoms, the pathophysiology of bipolar disorder (BD) remains unclear. BD is often misdiagnosed or tardily detected, leading to inadequate treatment and devastating consequences. The identification of objective biomarkers, such asfunctional and structural brain abnormalities of BD might improve diagnosis and help elucidate its pathophysiology, easily to detect and predict treatment response and prognosis. The development of diagnostic biomarkers for psychiatric disorders is a significant challenge and needed. Diagnosing psychiatric disorders are based on clinical observations of behavioral changes. Some biomarker i.e. gene, epigenetics, hormone and other blood markers, neuroimaging and neurophysiology are candidate of biomarker for BD.