PROFIL FITOKIMIA DAN UJI TOKSISITAS DAUN TUMBUHAN Aglaia odorata DENGAN METODE BRINE SHRIMP LETHALITY TEST
Main Author: | Ridho, Sahary Adha |
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Format: | Thesis NonPeerReviewed Book |
Bahasa: | eng |
Terbitan: |
, 2016
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Subjects: | |
Online Access: |
http://scholar.unand.ac.id/16371/1/Abstrak.pdf http://scholar.unand.ac.id/16371/2/Bab%201.pdf http://scholar.unand.ac.id/16371/3/Bab%20Akhir.pdf http://scholar.unand.ac.id/16371/4/Daftar%20Pustaka.pdf http://scholar.unand.ac.id/16371/5/Karya%20Ilmiah%20Utuh.pdf http://scholar.unand.ac.id/16371/ |
Daftar Isi:
- Toxicity and phytochemistry assay has been conducted on extracts and fractions of Aglaia odorata leaves using brine shrimp lethality test. Aglaia odorata is one of the plant that are found in Indonesia. To investigate Aglaia odorata leaves potential as anticancer, air-dried and powdered leaves were extracted with n-hexane, ethyl acetat, and metanol by using maceration method. Extract of ethyl acetat showed the highest toxicity with LC50 value is 125.89 mg/L. Extract of ethyl acetate was subjected to silica gel chromatography column with SGP (step gradient polarity) system using n-hexane, ethyl acetate, and methanol to afford 7 fractions. And then, each fractions was investigated its toxicity. Fraction 7 showed the highest toxicity with IC50 value is 204.17 mg/L. Keywords: Aglaia odorata, toxicity, brine shrimp lethality test