Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
| Main Authors: | Issa, Hamad H., Tanaka, Junichi, Rachmat, Rachmaniar, Setiawan, Andi, Trianto, Agus, Higa, Tatsuo |
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| Format: | Article PeerReviewed application/pdf |
| Terbitan: |
, 2005
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| Subjects: | |
| Online Access: |
http://eprints.undip.ac.id/430/1/marinedrugs-03-00078.pdf http://www.mdpi.com/1660-3397/3/3/78 http://eprints.undip.ac.id/430/ |
Daftar Isi:
- Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1-5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis.