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PENGARUH PEMBERIAN SEDUHAN KELOPAK BUNGA ROSELLA (Hibiscus sabdariffa) DOSIS BERTINGKAT SELAMA 30 HARI TERHADAP GAMBARAN HISTOLOGIS HEPAR TIKUS WISTAR

Main Author: Widyarini, Mela Kurnia
Format: Thesis NonPeerReviewed application/pdf
Terbitan: , 2010
Subjects:
RV Botanic
Thomsonian
and eclectic medicine
Online Access: http://eprints.undip.ac.id/23599/1/Mela.pdf
http://eprints.undip.ac.id/23599/
ctrlnum 23599
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title>PENGARUH PEMBERIAN SEDUHAN KELOPAK BUNGA ROSELLA (Hibiscus sabdariffa) DOSIS BERTINGKAT SELAMA 30 HARI TERHADAP GAMBARAN HISTOLOGIS HEPAR TIKUS WISTAR</title><creator>Widyarini, Mela Kurnia </creator><subject>RV Botanic, Thomsonian, and eclectic medicine</subject><description>Background : Hibiscus sabdariffa is one of the public health drink known as roselle tea. According to the result of previous research, it proved as an antioxidant, anticancer, antihypertension and decreasing cholesterol levels. Roselle (Hibiscus sabdariffa) will undergo metabolism process in the liver after absorbed by intestine. Liver is the main place for detoxication so it often damaged which marked histological structure changes.&#xD; Methods : The design of this research was Post Test Only Control Group, using 20 wistar male rats, divided randomly in 4 groups K : no treatment just given water; group P1 was given 40 mg/day roselle (Hibiscus sabdariffa) calyces steeping oral; group P2 was given 60 mg/day; group P3 was given 90 mg/day for 30 days for each group. Data was analyzed with Kruskal Wallis. The differences between groups were then analyzed with Mann Whitney &#xD; Result : Shapiro Wilk test result showed distribution of data was abnormal (p&lt;0,05) then analyzed with Kruskal Wallis test and this test showed significant difference (p=0,001). The Mann Whitney test result showed significant difference (p&lt;0,05) from each groups. &#xD; Conclusion : There were differences of liver histological appearance as parenchymatous degeneration, hidropic degeneration, up to necrosis between group which given roselle (Hibiscus sabdariffa) calyces steeping oral and control group, and there were differences of liver histological appearance among treatment group to each other.&#xD; &#xD; Keywords : Roselle (Hibiscus sabdariffa), liver, parenchymatous degeneration, hidropic degeneration, necrosis &#xD; </description><date>2010</date><type>Thesis:Thesis</type><type>PeerReview:NonPeerReviewed</type><type>File:application/pdf</type><identifier>http://eprints.undip.ac.id/23599/1/Mela.pdf</identifier><identifier>Widyarini, Mela Kurnia (2010) PENGARUH PEMBERIAN SEDUHAN KELOPAK BUNGA ROSELLA (Hibiscus sabdariffa) DOSIS BERTINGKAT SELAMA 30 HARI TERHADAP GAMBARAN HISTOLOGIS HEPAR TIKUS WISTAR. Undergraduate thesis, Faculty of Medicine.</identifier><relation>http://eprints.undip.ac.id/23599/</relation><recordID>23599</recordID></dc>
format Thesis:Thesis
Thesis
PeerReview:NonPeerReviewed
PeerReview
File:application/pdf
File
author Widyarini, Mela Kurnia
title PENGARUH PEMBERIAN SEDUHAN KELOPAK BUNGA ROSELLA (Hibiscus sabdariffa) DOSIS BERTINGKAT SELAMA 30 HARI TERHADAP GAMBARAN HISTOLOGIS HEPAR TIKUS WISTAR
publishDate 2010
topic RV Botanic
Thomsonian
and eclectic medicine
url http://eprints.undip.ac.id/23599/1/Mela.pdf
http://eprints.undip.ac.id/23599/
contents Background : Hibiscus sabdariffa is one of the public health drink known as roselle tea. According to the result of previous research, it proved as an antioxidant, anticancer, antihypertension and decreasing cholesterol levels. Roselle (Hibiscus sabdariffa) will undergo metabolism process in the liver after absorbed by intestine. Liver is the main place for detoxication so it often damaged which marked histological structure changes. Methods : The design of this research was Post Test Only Control Group, using 20 wistar male rats, divided randomly in 4 groups K : no treatment just given water; group P1 was given 40 mg/day roselle (Hibiscus sabdariffa) calyces steeping oral; group P2 was given 60 mg/day; group P3 was given 90 mg/day for 30 days for each group. Data was analyzed with Kruskal Wallis. The differences between groups were then analyzed with Mann Whitney Result : Shapiro Wilk test result showed distribution of data was abnormal (p<0,05) then analyzed with Kruskal Wallis test and this test showed significant difference (p=0,001). The Mann Whitney test result showed significant difference (p<0,05) from each groups. Conclusion : There were differences of liver histological appearance as parenchymatous degeneration, hidropic degeneration, up to necrosis between group which given roselle (Hibiscus sabdariffa) calyces steeping oral and control group, and there were differences of liver histological appearance among treatment group to each other. Keywords : Roselle (Hibiscus sabdariffa), liver, parenchymatous degeneration, hidropic degeneration, necrosis
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library_id 485
collection Diponegoro University Institutional Repository
repository_id 2852
city SEMARANG
province JAWA TENGAH
repoId IOS2852
first_indexed 2016-09-15T18:15:34Z
last_indexed 2016-09-22T21:01:28Z
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