PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
| Main Authors: | , Asep Indah Wuddi Arief, , dr. Pandit Sarosa, Sp.An-K |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2012
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/99574/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=56012 |
Daftar Isi:
- Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidocaine. Methods. A prospective, randomized double blind controlled trial study was performed in 101 patient (ASA I-II) undergoing general anesthesia with orotracheal intubation. Patient were randomly allocated into one of two groups to receive oropharyngeal lidocaine 2% 5 cc (group IO, n = 51) and intravenous lidocaine 2% 1,5 mg/bodyweight (Group IV, n = 50) 3 minute before orotracheal intubation. The incidence of increasing MAP, SBP, DBP, and HR > 20% was compared between the two groups. Results. The incidence of increasing MAP > 20% in IO group (29%) was significantly lower than IV group (56%) (p = 0,007), RR 0,52, CI 95% 0,32-0,85). The incidence of increasing SBP, DBP, and HR > 20% in IO group (27%, 29%, 9,8%) was significantly lower than IV group respectively (60%, 64%, 38%) (p = 0,007, p = 0,000, p = 0,001). Hemodynamic increase occur at 1 minute post orotracheal intubation and will return to basal at 3-10 minute post orotracheal intubation. Conclusion. Adminitration oropharyngeal lidocaine 2% 5 cc instillation was better in decreasing hemodynamic changes post orotracheal intubation compared with intravenous lidocaine 2% 1,5 mg/bodyweight.