PERBANDINGAN PENGARUH OKSITOSIN PROFILAKSIS SECARA INTRAVENA UMBILIKAL DAN INTRAMUSKULAR TERHADAP LAMA LAHIR PLASENTA DAN JUMLAH PERDARAHAN PASCASALIN
| Main Authors: | , Mohammad Zacky Arda, , Dr. Shofwal Widad, SpOG(K) |
|---|---|
| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2012
|
| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/98442/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=55159 |
Daftar Isi:
- Background: Indonesia is still listed as a country with the highest maternal mortality rate in Asia where obstetrical bleeding is the major cause of maternal morbidity and mortality. From all causes of maternal mortality, 80% due to uterine atony and 10% due to retained placenta. Cause of post partum haemorrhage due to retained placenta is poor management of third stage labor. One of procedure in the active management third stage labor for prevention of post partum hemorrhage is oxytocin injection. Oxytocin can be administered via the umbilical vein injection. Advantage of umbilical vein injection is reducing the length of the placenta release and lower the risk of post partum hemorrhage. Objective: To compare the effect of prophylactic oxytocin injection in umbilical vein and intramuscular related to length of placenta delivery and amount of bleeding in the third and fourth stage of labor, Research Design: randomized controlled trial. Methods: One hundred subjects, divided into 2 groups: treatment group and control group.The treatment group consisted of 50 patients who received umbilical vein injection of oxytocin during the third stage. The control group consisted of 50 patients who received intramuscular injection of oxytocin during the third stage. Oxytocin injections performed immediately after birth. Results: There were significant differences on the length of placenta release (p <0.001) that is 6,55±1,46 minutes in the treated group and 10,15±2,71 minutes in the control group. There are significant differences in the amount of bleeding the third stage (p <0.001) that is 140,10±32,39 ml in the umbilical vein group and 176,20± 58,34 ml in the intramuscular group. At forth stage bleeding, there were significant differences between treatment group and control group (p = 0.004) that is 33,80±16,55 ml in the umbilical vein group and 42,00±10,44 ml in the intramuscular group. Conclusion: Prophylactic oxytocin injection in normal delivery through umbilical vein can reduce bleeding on third and fourth stage of labor, as well can accelerate the release of the placenta compared with the intramuscular administration.