PERBANDINGAN STABILITAS HEMODINAMIK TOTAL INTRAVENOUS ANESTHESIA (TIVA) KONTINYU PADA METODE OPERASI WANITA (MOW) (Perbandingan antara Kombinasi Propofol 2 mg/kgbb/jam dan Ketamin 0,5mg/kgbb/jam dengan Kombinasi Propofol 2 mg/kgbb/jam dan Fentanyl 1 Î1⁄4g/kgbb/jam)
| Main Authors: | , SANDHIE PRASETYA, , DR. Sudadi, Dr, SpAn, KNA, |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2011
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/91135/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=53777 |
Daftar Isi:
- Background: Continuous TIVA technique using a combination of propofol and fentanyl has been commonly used in RSUP Sardjito. These techniques could provide adequate anesthesia, but often cause a variety of intraoperative hemodynamic changes. The combination of propofol and ketamine are expected to provide a comfortable anesthesia for surgery with a more stable hemodynamic changes. Methods: The study design was randomized controlled trial. The scope of the study were female patients who underwent tubal ligation sterilization operations with Metode Operasi Wanita (MOW) technique at the Instalasi Kontrasepsi Mantap RSUP. Dr. Sardjito Yogyakarta with continuous TIVA technique. Total 70 subjects that met criteria of inclusion were divided into two groups which consisted of 35 patients each. PK group used a combination of propofol 2 mg/kg and ketamine 0.5 mg/kg and were continued with propofol 2 mg/kg/hour and ketamine 0.5 mg/kg/hour intravenously. The PF group used a combination of propofol 2 mg / kg and fentanyl 1 mcg/kg and were continued with propofol 2 mg/kg/hour and fentanyl 1 mcg/kg/hour intravenously. Parameters of hemodynamic changes in systolic blood pressure (TDS), diastolic blood pressure (TDD), mean arterial pressure (TAR) and heart rate (DJ) were assessed at induction, incission and every 5 minutes until the operation was completed. Results: The change of hemodynamic parameters more than 10 % occurred in the PF group at the time of induction, after first incision and the fifth minute, in which the TDS decreased by 15.5 (7.26) %, TDD of 14.9 (9.39) %, TAR of 14.0 (8.34) %, DJ 14.2 (6.52) % whereas in group PK, TDS decreased by 4.3 (2.72) % (p = 0.000), TDD of 5.6 (3.18) % (p = 0.000), TAR of 4.6 (3.18) % (p =0.000) and DJ of 3.5(2.63) % (p = 0.000) at the time of induction. Conclusion: The hemodynamic stability of the PK group was better than the PF group.