PENGARUH PEMBERIAN CAMPURAN MADU, JINTAN HITAM, PROPOLIS DAN ROYAL JELI TERHADAP SEL �-PANKREAS DAN KADAR MALONDIALDEHID PADA TIKUS WISTAR PASCA PAPARAN STREPTOZOTOCI
| Main Authors: | , Drs. H. Sunyoto, B.Sc, Apt., , dr. Setyo Purwono.,M.Kes.,Sp.PD |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2011
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/89593/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=52213 |
Daftar Isi:
- Research Background: Hyperglycemic chronic could cause free radical. Free radical caused an increasing of oxidative stress, reducing the antioxidant, and an increasing of peroxidative lipid, and the damage of Î2 pancreas cell. The final product of peroxidative lipid was malondialdehid (MDA). The damage of Î2 pancreas cell decreased the insulin production so that it caused hyperglycemia chronic. The anti-oxidant activities of honey, black dill, propolis, and prodigal broodinging were expected to reduce free radical, so that they could reduce the MDA level and the amount of Î2 pancreas cell vacuole. Research Objectives: to indicate the influence of the mixture of 40% honey, 30% dill, 20% propolis, and 10% prodigal broodinging to the MDA level and the amount of Î2 pancreas cell vacuole. Research Method: Thirty white male Wistar hyperglycemic rat intraperitonially inducted with STZ (Group 2 â�� 6) and six normal rats. Groups 4, 5, and 6 were treated with the mixture of honey, black dill, propolis, and prodigal broodinging with the dosage 0,6