PERBANDINGAN PEMBERIAN EFEDRIN 30 Î1⁄4g/ KGBB IV DAN LIDOKAIN 2% 40 mg IV UNTUK MENGURANGI NYERI INDUKSI PROPOFOL 2 MG/KGBB IV PADA GENERAL ANESTESI
| Main Authors: | , dr. Mujahidin, , Dr. Yusmein Uyun, SpAn, KAO |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2011
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/88912/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51237 |
Daftar Isi:
- The administration of propofol often causes burning sensation in the area of injection. There have been efforts to reduce discomfort, however the result remain unsatisfactorily. The main purpose of this study is to find objective evidence of whether the administration of ephedrin 30Î1⁄4g/kgBB IV is more effective than 40mg 2% lidocain in order to reduce propofol 2mg/kgBB injection pain. This study was conducted in the double blind Randomized Controlled Trial (RCT). to 128 patients, with the range of age 18-60 years, physical status ASA I and II, BMI 17,5 â�� 24,5 kg/m2 which had been done elective surgery in Gedung Bedah Sentral Terpadu (GBST) RS DR. Sardjito Yogyakarta and other education network (RSUD Banyumas, RSUD Panembahan Senopati Bantul, RS Orthopedi Solo, RS Saras Husada Purworejo) which carried out 2-4 months, general anaesthesia has been done with endotracheal intubation technic. Subjects has been devided into 2 groups, group A (lidokain 40 mg) and group B (efedrin 30Î1⁄4g/ kgBB). All of the patients have been given at the vena sefalikabasalika with 18G needle and RL. After one of the drug has been given, the patient will be inducted with propofol 60 seconds later. The measurement of discomfort caused by propofol injection has been marked with discomfort scoring system (score 0-3), the blood pressure measurement has been taken before and after propofol administration. The results showed no statistically significant difference in the two study groups (2% lidocaine 40 mg IV vs ephedrine 30Î1⁄4g/kgbb IV) on pain response measured when patients received propofol 2mg/kgbb IV, p > 0.05 (P = 0.068) In group A there were 52 patients (81.3%), pain-free, while for group B there were 59 patients (92.2%). The pain response obtained was varies, in group A obtained a scale of 1-3, while in group B obtained a scale of 1-2. It can be concluded that administration of IV ephedrine 30Î1⁄4g/kgBB is not different significant effect compared with 2% lidocaine 40 mg IV to prevent response to pain during injection of propofol 2 mg / kg IV, P> 0.05 (P = 0.068), but clinically group B have the ability to eliminate pain in 59 patients (92,2%) compared with group A in 52 patients (81,3%), while the possibility of causing pain in group A were 12 patients (7,8%) and group B were 5 patients (18,7%).