The Diagnostic Accuracy Of Clinical And Blood Examination For Sepsis In Potentially Infected Neonates

Main Author: Perpustakaan UGM, i-lib
Format: Article NonPeerReviewed
Terbitan: [Yogyakarta] : Universitas Gadjah Mada , 2002
Subjects:
Online Access: https://repository.ugm.ac.id/25085/
http://i-lib.ugm.ac.id/jurnal/download.php?dataId=8068
Daftar Isi:
  • Ari Mulyani, D Setyowireni, Achmad Surjono - The diagnostic accuracy of clinical and blood examination for sepsis in potentially infected neonates Background: Neonatal sepsis remains a diagnostic challenge due to its nonspesific symptoms. Blood culture examination which is considered to be the gold standard, sometimes it is still a problem because takes time to get the result, expensive and not every health facility is able to perform. Objective: To evaluate the diagnostic accuracy of clinical symptoms, hematologic findings and C-Reactive Protein (CRP) in neonatal sepsis. Methods: Samples were taken from potentially infected neonates admitted to the Maternal-Perinatal Unit of Dr. Sardjito Hospital, Yogyakarta, between December 1st, 2000 to March 31st, 2001 using at least one of the criteria: prematurity (15,000/pL), premature rupture of the membrane (>24 hours), thick and cloudy amniotic fluid. Clinical symptoms, total white blood cell count, total neutrophil count, platelet count, CRP, and blood culture as gold standard were examined. Results: Among 99 neonates who were enrolled in this study, the sensitivity, specificity, positive predictive value and negative predictive value of clinical symptoms were 79.3%, 75.7%, 57.5%, and 89.9%, respectively