Uji aktivitas antioksidan jus buah mengkudu (Morinda citrifolia) dan perannya sebagai inhbitor advanced glycation end products (AGEs) akibat reaksi glikosilasi
| Main Author: | Perpustakaan UGM, i-lib |
|---|---|
| Format: | Article NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2005
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/18500/ http://i-lib.ugm.ac.id/jurnal/download.php?dataId=1291 |
Daftar Isi:
- Background: Mengkudu is a traditional plant with active compound that has antioxidant activity. Diabetes mellitus complication has causative link with AGEs formation that involves free radical. Objective: To know antioxidant activity of mengkudu and the role to inhibit AGEs formation. Methods: This experiment used pre and post test control group design. Antioxidant activity was determined by reacting the mengkudu juice with 2,4 dinitrophenylhydrazin (DNPH) and analyzed with spectrophotometer X=390 nm. AGEs absorbancy was measured every 48 hours until 20 days with spectrophotometer ?=340 nm. Dicarbonyl level was determined with DNPH method that was developed by Uchida and modified by Sadikin. Result: Antioxidant activity of 0.25 g/mI mengkudu juice (Morinda citrifolia) was 125.46±27.79%. Beside that, mengkudu juice can inhibit advanced glycation end products (AGEs) formation. Conclusion: formationMengkudu juice can decrease AGEs formation and has antioxidant activity. Key words: antioxidant - mengkudu juice - AGEs - glycosilation